Adrenal Venous Sampling: The Procedure and Result Conversation
Menopause & HormonesArticleUnderstand a referred investigation of adrenal-related high blood pressure, including the possibility of an incomplete result.

In this article
If a referral for blood-pressure investigation now includes an appointment in interventional radiology, ask the endocrine team to explain that next step. Get the reason for the procedure in writing, alongside the question its results should help answer.
This guide concerns a procedure already requested by your clinical team.
Before: settle the preparation with your service
Cambridge’s leaflet identifies blood-pressure medicines that can affect results, blood-thinning medicines that need advance discussion, allergies and previous reactions to contrast dye. The team also checks pregnancy status because the procedure uses X-rays.1
Contact the service before the appointment if any of those details need clarification. Send the names of your medicines, including aspirin, rather than deciding which ones count as blood thinners. Do not pause a prescription yourself.
Ask for one written plan covering what to take, any clinician-directed changes and when to resume a paused medicine. Confirm your own food and drink instructions, arrival details and the arrangements for getting home. Tell the team if an instruction conflicts with another clinician’s prescription.
During: tubes reach the adrenal veins
A radiologist uses local anesthetic at the groin and places a tube into a vein there. Smaller tubes reach the adrenal veins. Contrast dye checks their position before samples are taken. The groin tube is then removed and staff apply pressure.1
Tell staff if the procedure becomes uncomfortable. Additional pain relief can be given.1
Before consenting, ask the radiologist to explain the risks that matter for your circumstances and what the procedure can establish. Bring up difficulty lying in the required position when arranging the appointment.
After: recovery comes before the journey home
Staff monitor recovery, including blood pressure and the groin site. Cambridge requires someone to collect patients and take them home, without driving themselves or using public transport.1
Check your own service’s discharge and activity instructions before arranging the day. Ask what to do about bleeding or other concerns at home and which number works outside opening hours. Keep the written directions with the person helping you.
Results: an incomplete sample needs another discussion
Sometimes a sample cannot be obtained or does not provide enough information for diagnosis. The team then discusses repeating the procedure or another test.1
And an appointment for sampling does not settle what treatment comes next. Confirm which clinician will interpret the results, when you will discuss them and whom to contact if that conversation has not been arranged. Ask what uncertainty remains and how the findings affect the options being considered.
My Body Changed. Now What? includes a Visit Brief. Use it to collect your referral question and appointment questions beside the endocrine team’s instructions. See the menopause and hormones playbook.
This article is for general educational purposes only and is not medical advice. It isn't a substitute for diagnosis or treatment from a qualified healthcare professional who knows your health history. Please don't ignore professional advice or delay getting care because of something you read here. If you think you may be having a medical emergency, call 911 or your local emergency number right away. Girl Playbook does not endorse any specific product, test, or provider.
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Sources
The research behind this article, in the order it’s cited. How we source our articles.
- Cambridge University Hospitals NHS Foundation Trust, 2026Adrenal venous sampling – A guide for patients (opens in a new tab)abcdef
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