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One Side of My Face Flushes and Sweats: What Is a Harlequin Sign?

Understand the descriptive term and prepare for an assessment of a changed pattern.

Adult woman in a pale pink blouse organizing a blank notebook and cream appointment folder.
In this article
  1. What needs emergency attention?
  2. What does “Harlequin sign” describe?
  3. Is the sign the same as a diagnosis?
  4. What might the assessment involve?
  5. Will it need treatment?

If one side of your face looks flushed and damp while the other looks unchanged, you may find yourself checking the mirror repeatedly. Describe that difference to a healthcare professional. A name for the pattern can help you ask questions without deciding its cause yourself.

What needs emergency attention?

Sudden facial drooping, arm weakness or speech problems can be signs of stroke. In the UK, call 999 immediately for suspected stroke, including signs within the past 24 hours that have stopped. Do not drive yourself to A&E.1

Do not explain those symptoms away as a sweating problem or wait to complete appointment notes.

What does “Harlequin sign” describe?

It describes redness or darkening on one side of the face or body while the other side looks pale or unchanged. Sweating and warmth can accompany the color change. Cleveland Clinic2 advises a healthcare assessment if you notice this pattern.2

Tell the clinician which areas change and when you first noticed the difference. If you already have a photograph taken during an episode, ask whether it would be useful to show it. You do not need to trigger another episode to prepare for the visit.

Is the sign the same as a diagnosis?

No. The sign can occur with different conditions, including Harlequin syndrome, which affects the sympathetic nervous system. Cleveland Clinic2 also describes a possible relationship with Horner syndrome. The visible pattern alone does not tell you which cause applies.2

Ask: “What does this pattern suggest in my case, and what else do you need to check?” Mention other changes you have noticed, even if you are unsure whether they are connected.

What might the assessment involve?

Cleveland Clinic2 describes a physical examination and symptom questions, with possible tests to rule out other conditions. An underlying condition can sometimes be responsible. Ask which findings the clinician wants to investigate and how you will receive the results.2

Bring your medicine list and details of any recent procedures. Explain whether the episodes interfere with work, exercise or being around other people. That helps you describe the concern you want addressed.

Will it need treatment?

Treatment depends on the cause and may not be necessary. If treatment is proposed, ask what it aims to improve and how the clinician will assess the result. Avoid choosing a sweat treatment before the pattern has been evaluated.2

Arms Up includes a Fresh Log and visit script. Use them to organize your observations and the questions you want answered. Keep the assessment plan and follow-up details with those notes.

This article is for general educational purposes only and is not medical advice. It isn't a substitute for diagnosis or treatment from a qualified healthcare professional who knows your health history. Please don't ignore professional advice or delay getting care because of something you read here. If you think you may be having a medical emergency, call 911 or your local emergency number right away. Girl Playbook does not endorse any specific product, test, or provider.

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Girl Playbook sells this book. It provides education and worksheets, not individualized medical care.

Sources

The research behind this article, in the order it’s cited. How we source our articles.

  1. NHS, 2024Symptoms of a stroke (opens in a new tab)↩
  2. Cleveland Clinic, 2024Harlequin Sign (opens in a new tab)abcdefg

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