PRP Injections for Orgasm, Arousal or Dryness: What Sexual Medicine Experts Say

Med spas and some practices advertise injections of platelet-rich plasma (PRP), made from your own blood, into the clitoris or vaginal wall, often under catchy names. They’re promoted for stronger orgasms, arousal, dryness or leaks. Stem cell shots and energy devices (laser, radiofrequency, shockwave) are sold for similar goals.

What the experts concluded

The Fifth International Consultation on Sexual Medicine reviewed these “regenerative” treatments in 2024. Its findings:¹

• These treatments are widely available for purchase, and their promise and availability have outpaced the research.
• They appear generally safe and well tolerated.
• Studies of stem cells, PRP, electrical stimulation, light therapy, radiofrequency, laser and shockwave for sexual problems have significant design weaknesses.
• Even the best-studied option for women, vaginal CO2 laser for menopause symptoms, didn’t have strong enough evidence for the experts to agree on recommending it.

Bottom line from the panel: the evidence is insufficient to support using these treatments for sexual problems right now.¹

What does work for menopause dryness and pain

The Menopause² Society notes that vaginal and urinary symptoms of menopause affect a large share of women, are often undertreated, and can usually be managed.² Options with evidence include:²

• Over-the-counter moisturizers and lubricants, often enough for mild symptoms. See our guide to moisturizer vs. lubricant.
• Vaginal estrogen or vaginal DHEA (prasterone). See prasterone details.
• Ospemifene, a daily pill. See ospemifene checks.
• Systemic hormone therapy.

For low desire, our article on flibanserin covers an approved option, and vaginal laser evidence and the FDA warning on tightening devices cover energy devices.

If you’re still considering an injection

1. What published studies support this for my problem, and were they controlled?
2. Who performs it, and what are their credentials in gynecology or sexual medicine?
3. What’s the total cost, how many sessions, and what happens if it doesn’t work?
4. What are the risks, and who handles complications?

Try: “I’ve seen ads for PRP injections to improve orgasm. Before I spend money, what proven treatments should I try for my dryness and pain with sex?”

Down There, Decoded includes a Down-There Log and a See script for appointments. Use them to note your symptoms and what you’ve tried before asking about any new treatment. Explore the intimate-health playbook.