Caffeine Shampoo for Thinning Hair: What the Evidence Shows for Women
HairArticleCaffeine shampoos and scalp tonics promise to wake up sleepy follicles. Lab studies on hair follicles are intriguing, but the main clinical trial was in men, wasn't blinded and was funded by the maker. Here is how to weigh it.

In this article
Caffeine shampoos and leave-in tonics are marketed to women with thinning hair, often with claims about energizing follicles. Here is what the research shows.
The lab studies
In a 2014 study, researchers grew human scalp hair follicles from men and women in lab dishes. Caffeine lengthened hair shafts and kept follicles in the growth phase longer, and follicles from women responded more strongly than those from men.1
That’s interesting, but follicles in a dish aren’t a scalp on a person. Lab results don’t show how much caffeine reaches follicles from a shampoo that’s rinsed off after a minute or two.
The clinical trial
The main trial compared a 0.2% caffeine leave-in liquid with 5% minoxidil in 210 men with pattern hair loss for 6 months.2
- The proportion of hairs in the growth phase improved by about 11.7% with minoxidil and 10.6% with caffeine, and the authors concluded caffeine was not inferior.2
- The study was open-label: participants and examiners knew which product was used. The authors listed this as a limitation that could cause bias.2
- One author was an employee of the company that sponsored the study.2
- It tested a leave-in liquid used twice daily, not a shampoo, and it included only men.2
How this compares with proven options
The trial authors noted that minoxidil solution is an approved treatment for pattern hair loss in women.2 Our guide to topical minoxidil explains how it’s used. Other popular options with limited evidence include rosemary oil and scalp massagers.
If you want to try caffeine
- Leave-in products match what was studied better than shampoos.
- Keep using proven treatments if your clinician recommended them.
- Take photos monthly in the same light, and judge after several months.
- Stop if your scalp gets irritated.
Get the cause checked
Thinning can come from pattern hair loss, shedding after illness or stress, thyroid problems, low iron or medicines. Our article on why hair thins explains the causes a clinician may check.
Try: “My part is widening and I’ve been using a caffeine shampoo. Should we check iron and thyroid, and would minoxidil be a better option for me?”
Hair, Everywhere includes a Hair Check, a monthly Hair Log and a visit script. Use them to track photos, shedding and products over time. See the book.
This article is for general educational purposes only and is not medical advice. It isn't a substitute for diagnosis or treatment from a qualified healthcare professional who knows your health history. Please don't ignore professional advice or delay getting care because of something you read here. Sudden hair loss, patchy bald spots, scalp pain, scaling or redness should be checked by a clinician. If you think you may be having a medical emergency, call 911 or your local emergency number right away. This article discusses a category of product and published research. It does not evaluate any particular brand or product. Girl Playbook does not endorse any specific product, test, or provider.
Girl Playbook sells this book. It provides education and worksheets, not individualized medical care.
Sources
The research behind this article, in the order it’s cited. How we source our articles.
- British Journal of Dermatology (abstract via Europe PMC), 2014Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor-β2/insulin-like growth factor-1-mediated regulation of the hair cycle in male and female human hair follicles in vitro (opens in a new tab)↩
- Skin Pharmacology and Physiology (full text via PubMed Central), 2017An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia (opens in a new tab)abcdef
Spotted something out of date? Tell us and we’ll check it.


