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A Mouth Sore That Won't Heal: The Two-Week Rule and Oral Cancer Signs

Most mouth sores heal in days. The National Institute of Dental and Craniofacial Research says any sore, lump, white or red patch, or numbness that lasts more than two weeks should be checked by a dentist or doctor. Oral cancer is less common in women than men, but it most often occurs after 40, and dentures that suddenly fit poorly can be one sign.

Woman in her sixties at a bathroom mirror gently pulling her lower lip down to look inside her mouth, with good lighting and a calm, attentive expression.
In this article
  1. The two-week rule
  2. Who’s at higher risk
  3. What the check involves
  4. Common look-alikes

Canker sores, bitten cheeks and denture rubs usually heal within days. Oral cancer can start on the tongue, gums, cheek lining, floor of the mouth or the throat behind the mouth.1 It’s more common in men, but it most often occurs after 40, and women get it too.1

The two-week rule

The National Institute of Dental and Craniofacial Research (NIDCR)1 says to see a dentist or doctor if any of these lasts more than two weeks:1

  • A sore, irritation, lump or thick patch in your mouth, lip or throat
  • A white or red patch in your mouth
  • A persistent sore throat, a feeling that something is stuck, or hoarseness
  • A lump in the neck
  • Trouble chewing, swallowing, speaking or moving your jaw or tongue
  • Jaw swelling that makes dentures fit poorly
  • Pain or bleeding in the mouth
  • Numbness in the tongue or mouth
  • Ear pain

Early detection matters because oral cancer can spread quickly.1

Who’s at higher risk

  • Tobacco in any form, including e-cigarettes, and heavy alcohol use, especially together1
  • HPV infection, which causes most throat cancers1
  • Sun exposure for lip cancer1
  • A diet low in fruits and vegetables1

What the check involves

An oral cancer exam is painless and takes a few minutes. Your dentist or hygienist checks your face, neck, lips, whole mouth and the back of your throat.1 Ask for it at your regular checkup. If something looks unusual, you may be referred for a biopsy. Our guides to oral biopsy questions, leukoplakia follow-up and screening light devices explain next steps.

Common look-alikes

Many sores are harmless, which is why the two-week rule helps. See our guides to canker sores, a white tongue, cracked mouth corners and lip sun damage.

Try: “I’ve had a sore on the side of my tongue for three weeks. Can you examine it and tell me whether it needs a biopsy?”

Is It My Breath? includes a visit script. Use it to note when the sore started, its size and any changes before your appointment.

This article is for general educational purposes only and is not medical or dental advice. It isn't a substitute for diagnosis or treatment from a qualified healthcare professional who knows your health history. Please don't wait for a sore to get worse before having it checked. Trouble breathing, rapidly increasing swelling of the face or neck, or bleeding that won't stop needs emergency care. If you think you may be having a medical emergency, call 911 or your local emergency number right away. This article discusses federal health guidance. Girl Playbook does not endorse any specific product, test, or provider.

Read our health disclaimer

Girl Playbook sells this book. It provides education and worksheets, not individualized medical care.

Sources

The research behind this article, in the order it’s cited. How we source our articles.

  1. National Institute of Dental and Craniofacial ResearchOral Cancer (opens in a new tab)abcdefghij

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