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What Is a Stomach Ulcer?H. pylori and Ibuprofen

The upper-belly pain and early fullness of a peptic ulcer, why H. pylori bacteria and regular ibuprofen or aspirin are the two main causes, how it's tested and treated, and the signs of bleeding that need urgent care.

In this article
  1. Symptoms
  2. What causes it
  3. How it’s found
  4. Treatment
  5. Bleeding, the urgent part
  6. When to get checked

It’s a gnawing in the upper belly that shows up between meals, or in the middle of the night. A bite of food takes it away, or makes it worse. You’ve been popping ibuprofen for back pain most days for months, and now you’re also getting full after a few bites. You assume it’s reflux, and you’ve started eating less.

Symptoms

The NIDDK1 lists pain or discomfort in the upper abdomen, feeling full too soon while eating, nausea, vomiting, bloating and belching. Many people have no symptoms at first. See heartburn and GERD and nausea after eating for look-alikes.

What causes it

H. pylori is a bacterial infection. The NIDDK1 says NSAIDs, such as aspirin, ibuprofen and naproxen, are another common cause because they make the stomach lining more prone to damage and ulcers. It lists corticosteroids, antidepressants and some conditions among less common causes.

If you take ibuprofen or similar medicines most days, mention it to your clinician, who can look at your options. Ask before changing a prescribed medicine.

How it’s found

The NIDDK2 lists several tests: a urea breath test, where you swallow a capsule, liquid or pudding that contains specially labeled urea and your breath is checked for the carbon dioxide the bacteria make, a stool test, a blood test, an upper endoscopy with a camera and tissue samples, and an upper GI series with barium X-rays.

Treatment

The NIDDK3 says doctors prescribe acid-reducing medicines, proton pump inhibitors (PPIs) or H2 blockers. For H. pylori, they typically combine two or more antibiotics with a PPI, and the NIDDK says to finish the entire course, because stopping early lets bacteria survive and develop resistance. It says testing at least 4 weeks after you finish the antibiotics confirms the infection is gone.

If NSAIDs caused it, your doctor may recommend changing your medicines, switching, lowering the dose or taking a PPI alongside. The NIDDK3 says quitting smoking helps, since smoking can slow ulcer healing.

Bleeding, the urgent part

The NIDDK1 says to contact a doctor immediately for black or tarry stool, or red or maroon blood mixed with stool, or sudden, sharp or severe abdominal pain that doesn’t go away. Other warning signs include vomiting blood, dizziness, fainting and a rapid pulse.

The play

Try this: a pain-and-pills note

For two weeks, write down when the pain comes (before, during or after meals, at night), what it feels like, and what eases it.

List every medicine you take, including ibuprofen, naproxen, aspirin, steroids and antidepressants, with how often.

Bring it to your clinician and ask about H. pylori testing.

When to get checked

Don’t wait if

  1. Urgent

    Get urgent care for black or tarry stool, vomiting blood, sudden severe belly pain, dizziness or fainting.

Book an appointment if any of these fit:

  • Upper belly pain or burning keeps coming back
  • You feel full after only a few bites
  • You take ibuprofen, naproxen or aspirin regularly and have stomach symptoms
  • You’ve been treated for H. pylori and haven’t been retested

Pain that comes and goes isn’t always acid. Test before you guess.

Black or tarry stools, red or maroon blood in your stool, vomiting blood, sudden severe belly pain, dizziness or fainting need urgent medical care. Don't stop prescribed medicines without talking to a clinician.

This article is for general educational purposes only and is not medical advice. It isn't a substitute for diagnosis or treatment from a qualified healthcare professional who knows your health history. Please don't ignore professional advice or delay getting care because of something you read here. If you think you may be having a medical emergency, call 911 or your local emergency number right away. Girl Playbook does not endorse any specific product, test, or provider.

Read our health disclaimer

Girl Playbook sells this book. It provides education and worksheets, not individualized medical care.

Sources

The research behind this article, in the order it’s cited. How we source our articles.

  1. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Symptoms & Causes of Peptic Ulcers (opens in a new tab)abcd
  2. NIDDKDiagnosis of Peptic Ulcers (opens in a new tab)↩
  3. NIDDKTreatment for Peptic Ulcers (opens in a new tab)ab

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